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Effect of Me-Indoxam (A,B) and RO092906A (C,D) on fMLF-induced vascular endothelial growth factor (VEGF)-A and CXCL8/IL-8 release from PMNs. Cells were preincubated (37°C, 20 min) with or without Me-Indoxam and RO092906A (0.1 µM) and then stimulated (37°C, 1–6 h,) with fMLF (50 nM). VEGF-A (A–C) and CXCL8/IL-8 (B–D) release was determined by ELISA. Data are the mean ± SD of eight different preparations of PMNs. *p < 0.05 vs. fMLF alone.
