Table 3.
Linear and logistic regression for the relationship between vessel characteristics and fractional flow reserve.
| Per-vessel analysis (n=407) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Univariable linear regression | Univariable logistic regression | Multivariable logistic regressiona | |||||||
| B | SE | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | |
| Diffuseness measures: | |||||||||
| Log % PD | −0.058 | 0.010 | <0.001 | 3.11 | 1.98–4.89 | <0.001 | 1.58 | 1.005–2.48 | 0.048 |
| Other CCTA measures: | |||||||||
| Diameter stenosis, % | −0.004 | 0.0004 | <0.001 | 1.07 | 1.05–1.09 | <0.001 | |||
| Area stenosis, % | −0.003 | 0.0003 | <0.001 | 1.06 | 1.04–1.08 | <0.001 | |||
| Minimal lumen diameter, mmb | 0.126 | 0.011 | <0.001 | 0.08 | 0.04–0.18 | <0.001 | 0.12 | 0.06–0.25 | <0.001 |
| Minimal lumen area, mm2 | 0.038 | 0.004 | <0.001 | 0.40 | 0.30–0.54 | <0.001 | |||
| % APV | −0.005 | 0.001 | <0.001 | 1.08 | 1.06–1.11 | <0.001 | |||
| PRb | −0.112 | 0.012 | <0.001 | 10.31 | 6.35–16.72 | <0.001 | 7.21 | 4.02–12.91 | <0.001 |
| LAPb | −0.115 | 0.014 | <0.001 | 12.90 | 5.39–30.84 | <0.001 | 2.64 | 1.38–5.04 | 0.003 |
| SC | −0.062 | 0.017 | <0.001 | 3.89 | 2.04–7.41 | <0.001 | |||
Adjusted odds ratios retained from backward stepwise logistic regression are reported.
Minimal lumen diameter, positive remodeling, and low attenuation plaque were retained in backward stepwise logistic regression.
Log % PD, logarithmically transformed percent plaque diffuseness; % APV, percent aggregate plaque volume; PR, positive remodeling; LAP, low attenuation plaque; SC, spotty calcifications; B, unstandardized coefficient; SE, standard error; OR, odds ratio.