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. 2016 Jun 15;97(6):1333–1344. doi: 10.1099/jgv.0.000457

Fig. 2.

Fig. 2.

BLI receptor-binding assays of egg-propagated H3N2 viruses from 2013–2014 and 2015–2016 seasons and cell culture-propagated H3N2 viruses to 3-SLN and 6-SLN receptor-analogues. Binding curves for egg-propagated Switz13e, CVV X-223 and RG /Vic361e viruses with AA substitutions S219F or I226N to 3-SLN (2a) analogue compared with Vic361e; binding curves for Switz13e, its CVVs X-247 and NIB-88, and RG/Vic361e viruses with AA substitutions S219F or I226N to 6-SLN (2b) receptor-analogue compared with Vic361e; binding curves for exclusively cell culture680 propagated Vic361c and Switz13c, and RG/Vic361c virus bearing AA substitution H156R to 6-SLN receptor-analogue (2c). Viruses were assayed at a concentration of 100 pM based on the nucleoprotein content of purified virus.