Figure 1.

Diagram illustrating the four definitions of refractory AML (acute myeloid leukemia) used in this study. C1: course 1; C2: course 2; CR: complete remission; RES: resistant disease with failure to achieve a complete remission after C1; REF1: those deemed to have had a minor or no response to IC with more than 15% blasts and a less than 50% proportional reduction in blast percentage after C1; REF2: failure to achieve a complete remission after two courses of IC; PR: those deemed to have had a partial response after C1 with fewer than 15% blasts or a greater than 50% proportional reduction in blast percentage.