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. Author manuscript; available in PMC: 2018 Mar 9.
Published in final edited form as: Cell. 2017 Mar 9;168(6):960–976. doi: 10.1016/j.cell.2017.02.004

Figure 1. mTORC1 and mTORC2.

Figure 1

(A) The mTORC1 and mTORC2 signaling pathways.

(B) mTORC1 subunits and respective binding sites on mTOR. The FKBP12-rapamycin. The 5.9 Å cryo-EM structure of mTORC1 (without DEPTOR and PRAS40, PDB ID: 5FLC) from is depicted as a space filling model and colored by subunit.

(C) mTORC2 subunits and respective binding sites on mTOR.