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. 2017 Apr 18;12(4):e0175274. doi: 10.1371/journal.pone.0175274

Table 1. Demographic, clinical and serological data of GD patients with moderate-to-severe GO and without GO.

Moderate-to-severe GO (n = 21) Without GO (n = 21)
Females, n (%) 15 (71.4) 17 (81)
Males, n (%) 6 (28.6) 4 (19)
Age, y (median) 57 (20–77) 44 (26–69)
Smokers, n (%) 9 (42.8) 3 (14.3)
Duration GD, month (median) 14 (3–108) 21 (10–35) 0.018
TRAb, lU/L (reference range, <1.8) 19.9 (3.7–156.4) <0.9 (<0.9–4.9) <0.001
Radioiodine treatment, n (%) 5 (23.8) 0 (0) 0.019
Thyroid surgery, n (%) 1 (4.8) 1 (4.8) 1
TSH, mlU/L (median; reference range, 0.5–3.6) 0.05 (0.01–1.7) 0.88 (0.03–4.34) <0.001
Serum FT4, pmol/L (reference range, 8–21) 17.3 (10.1–49.2) 13.5 (11.4–21.3) 0.004
Serum FT3, pmol/L (reference range, 3.6–8.3) 7.4 (4.4–20.0) 5.4 (4.5–8.6) 0.005