Table 2. Percent of cells in different phase of cell cycle at different time interval in treated (DOX: Doxorubicin, PATA: Paclitaxel, SLCA B, SLCA C) and untreated (CNT-Control) cells.
Time | Treatment | G0 | G1 | S | G2 | M |
---|---|---|---|---|---|---|
6 h | CNT | 0 | 34.91±3.95 | 48.42±0.08 | 8.22±4.67 | 8.45±0.81 |
DOX | 3.28±1.26 | 8.87±0.04 | 20.27±3.17 | 59.33±5.10 | 8.24±3.15 | |
PATA | 2.05±1.97 | 9.12±0.86 | 11.57±2.28 | 51.39±3.78 | 25.86±2.60 | |
SLCA C | 8.47±2.20 | 51.67±0.55 | 32.06±0.83 | 6.66±0.72 | 1.13±0.10 | |
SLCA B | 0.52±0.21 | 56.21±4.99 | 33.81±3.58 | 6.55±0.23 | 2.89±1.38 | |
12h | CNT | 4.97±0.00 | 7.13±0.30 | 6.86±0.02 | 6.88±0.11 | 74.15±0.16 |
DOX | 54.92±3.59 | 37.34±0.76 | 2.37±0.03 | 5.54±2.45 | 2.82±2.37 | |
PATA | 1.78±0.14 | 9.46±0.33 | 14.52±2.01 | 45.73±3.92 | 28.50±1.73 | |
SLCA C | 4.21±3.90 | 54.33±2.02 | 32.72±0.90 | 7.7±0.62 | 1.03±0.35 | |
SLCA B | 2.71±1.54 | 52.30±0.60 | 31.71±2.40 | 9.31±1.31 | 3.96±3.24 | |
18h | CNT | 1.63±0.35 | 4.68±0.01 | 4.66±0.01 | 4.74±0.10 | 84.29±0.25 |
DOX | 54.70±2.44 | 34.98±0.91 | 2.69±0.51 | 4.91±0.61 | 2.71±2.23 | |
PATA | 2.43±0.33 | 10.85±1.15 | 12.02±1.82 | 52.21±2.52 | 22.47±0.12 | |
SLCA C | 3.49±0.15 | 55.33±2.20 | 31.14±3.04 | 9.17±1.91 | 0.86±0.92 | |
SLCA B | 5.69±5.28 | 53.21±1.68 | 32.27±0.88 | 7.50±2.61 | 1.32±0.11 | |
24h | CNT | 1.565±0.35 | 2.02±0.25 | 5.34±0.62 | 2.32±0.02 | 88.74±0.49 |
DOX | 54.70±3.20 | 35.61±4.55 | 3.03±1.35 | 4.01±4.03 | 2.63±2.37 | |
PATA | 0.29±0.28 | 15.55±1.28 | 7.10±1.21 | 52.87±2.55 | 24.17±2.34 | |
SLCA C | 0.17±0.25 | 55.24±0.21 | 35.52±0.80 | 8.60±0.35 | 0.45±0.49 | |
SLCA B | 0.09±0.00 | 53.94±2.01 | 27.45±1.71 | 16.99±4.43 | 1.52±0.71 |
The darkened numbers indicate the percentage of cells arrested in different phases of cell cycle.
The data is mean ± SD of three independent experiments.