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. 2017 Apr 18;12(4):e0176072. doi: 10.1371/journal.pone.0176072

Table 3. MICA–HLA-B haplotype frequencies and relative LD values (D’) for haplotypes with a frequency exceeding 1% in all samples (n = 346), and comparison with healthy subjects.

Haplotype Renal Healthy subjects
(Ribas et al., 2008)[17]
n % D' p LD n % D' p LD
MICA*009-B*51 54 7.80% 0.775 0 33 8.09% 0.75 0
MICA*004-B*44 42 6.07% 0.540 0 24 5.88% 0.47 0
MICA*002-B*35 39 5.64% 0.439 0 25 6.13% 0.54 0
MICA*008-B*07 38 5.49% 0.801 0 25 6.13% 0.86 0
MICA*008-B*08 36 5.20% 0.844 0 24 5.88% 0.85 0
MICA*010-B*15 36 5.20% 0.762 0 24 5.88% 0.81 0
MICA*018-B*18 26 3.76% 0.803 0 15 3.68% 0.93 0
MICA*002-B*39 24 3.47% 1.000 0 18 4.41% 1.00 0
MICA*002-B*38 23 3.32% 1.000 0 10 2.45% 1.00 0
MICA*008-B*44 22 3.18% 0.130 0.0301 20 4.90% 0.26 0.0017
MICA*004-B*49 21 3.03% 0.947 0 9 2.21% 1.00 0
MICA*016-B*35 21 3.03% 0.903 0 7 1.72% 1.00 0
MICA*011-B*14 20 2.89% 0.951 0 19 4.66% 1.00 0
MICA*008-B*15 18 2.60% 0.113 0.0852 9 2.21% 20.12 0.6207
MICA*007-B*27 16 2.31% 0.939 0 11 2.70% 1.00 0
MICA*004-B*42 15 2.17% 1.000 0 5 1.23% 1.00 0
MICA*002-B*58 14 2.02% 0.920 0 9 2.21% 1.00 0
MICA*017-B*57 13 1.88% 0.927 0 7 1.72% 1.00 0
MICA*004-B*41 12 1.73% 0.910 0 6 1.47% 1.00 0
MICA*009-B*50 12 1.73% 0.659 0 5 1.23% 0.81 0
MICA*008-B*40 11 1.59% 0.113 0.1842 7 1.72% 0.38 0.0158
MICA*009-B*35 10 1.45% -0.002 0.9938 6 1.47% 0.01 0.8052
MICA*008-B*13 9 1.30% 0.768 0 8 1.96% 0.85 0
Other** 160 23.12% 82 20.10%

**Haplotypes with frequency below 1%;

D’ = Relative linkage disequilibrium value; Only haplotypes in attraction (D' = 1 and D'<1) are shown. Healthy subjects described by Ribas et al., (2008)[17];