Table 3. MICA–HLA-B haplotype frequencies and relative LD values (D’) for haplotypes with a frequency exceeding 1% in all samples (n = 346), and comparison with healthy subjects.
Haplotype | Renal | Healthy subjects (Ribas et al., 2008)[17] |
||||||
---|---|---|---|---|---|---|---|---|
n | % | D' | p LD | n | % | D' | p LD | |
MICA*009-B*51 | 54 | 7.80% | 0.775 | 0 | 33 | 8.09% | 0.75 | 0 |
MICA*004-B*44 | 42 | 6.07% | 0.540 | 0 | 24 | 5.88% | 0.47 | 0 |
MICA*002-B*35 | 39 | 5.64% | 0.439 | 0 | 25 | 6.13% | 0.54 | 0 |
MICA*008-B*07 | 38 | 5.49% | 0.801 | 0 | 25 | 6.13% | 0.86 | 0 |
MICA*008-B*08 | 36 | 5.20% | 0.844 | 0 | 24 | 5.88% | 0.85 | 0 |
MICA*010-B*15 | 36 | 5.20% | 0.762 | 0 | 24 | 5.88% | 0.81 | 0 |
MICA*018-B*18 | 26 | 3.76% | 0.803 | 0 | 15 | 3.68% | 0.93 | 0 |
MICA*002-B*39 | 24 | 3.47% | 1.000 | 0 | 18 | 4.41% | 1.00 | 0 |
MICA*002-B*38 | 23 | 3.32% | 1.000 | 0 | 10 | 2.45% | 1.00 | 0 |
MICA*008-B*44 | 22 | 3.18% | 0.130 | 0.0301 | 20 | 4.90% | 0.26 | 0.0017 |
MICA*004-B*49 | 21 | 3.03% | 0.947 | 0 | 9 | 2.21% | 1.00 | 0 |
MICA*016-B*35 | 21 | 3.03% | 0.903 | 0 | 7 | 1.72% | 1.00 | 0 |
MICA*011-B*14 | 20 | 2.89% | 0.951 | 0 | 19 | 4.66% | 1.00 | 0 |
MICA*008-B*15 | 18 | 2.60% | 0.113 | 0.0852 | 9 | 2.21% | 20.12 | 0.6207 |
MICA*007-B*27 | 16 | 2.31% | 0.939 | 0 | 11 | 2.70% | 1.00 | 0 |
MICA*004-B*42 | 15 | 2.17% | 1.000 | 0 | 5 | 1.23% | 1.00 | 0 |
MICA*002-B*58 | 14 | 2.02% | 0.920 | 0 | 9 | 2.21% | 1.00 | 0 |
MICA*017-B*57 | 13 | 1.88% | 0.927 | 0 | 7 | 1.72% | 1.00 | 0 |
MICA*004-B*41 | 12 | 1.73% | 0.910 | 0 | 6 | 1.47% | 1.00 | 0 |
MICA*009-B*50 | 12 | 1.73% | 0.659 | 0 | 5 | 1.23% | 0.81 | 0 |
MICA*008-B*40 | 11 | 1.59% | 0.113 | 0.1842 | 7 | 1.72% | 0.38 | 0.0158 |
MICA*009-B*35 | 10 | 1.45% | -0.002 | 0.9938 | 6 | 1.47% | 0.01 | 0.8052 |
MICA*008-B*13 | 9 | 1.30% | 0.768 | 0 | 8 | 1.96% | 0.85 | 0 |
Other** | 160 | 23.12% | 82 | 20.10% |
**Haplotypes with frequency below 1%;
D’ = Relative linkage disequilibrium value; Only haplotypes in attraction (D' = 1 and D'<1) are shown. Healthy subjects described by Ribas et al., (2008)[17];