Table 3. Sensitivity of ELISA for antibodies to Hcp1 and OPS in different groups of melioidosis patients.
The results were obtained from OD450 values of sera from melioidosis patients at serum dilution of 1:2000. The cut-off values with Thai healthy donors as controls were used at specificity of 95% for each assay.
| Group of patients | No. of patients (%) | Hcp1-ELISA | OPS-ELISA | ||||
|---|---|---|---|---|---|---|---|
| No. of positive | Sensitivity (%) | P-value | No. of positive | Sensitivity (%) | P-value | ||
| DM | 134 (67.0) | 117 | 87.3 | 0.004 | 118 | 88.1 | <0.001 |
| Non-DM | 66 (33.0) | 46 | 69.7 | 40 | 60.6 | ||
| Bacteremia | 105 (52.5) | 87 | 82.9 | 0.654 | 88 | 83.8 | 0.085 |
| Non-bacteremia | 95 (47.5) | 76 | 80.0 | 70 | 73.7 | ||
| Died | 64 (32.0) | 50 | 78.1 | 0.629 | 50 | 78.1 | 0.91 |
| Survived | 134 (67.0) | 111 | 82.8 | 106 | 79.1 | ||
| Unknown | 2 (1.0) | 2 | 100 | 2 | 100 | ||
Bold represents statistical significance