Skip to main content
. Author manuscript; available in PMC: 2017 May 14.
Published in final edited form as: Pediatr Res. 2016 Nov 14;81(4):565–571. doi: 10.1038/pr.2016.240

Figure 1.

Figure 1

Respiratory System Resistance (Rrs) and Specific Respiratory System Compliance (sCrs) and responses to methacholine in mechanically ventilated mice at P21. (a) Significant increases in Rrs were observed at higher methacholine doses of both groups who received intermittent hyperoxia (CIHO/E, dashed line closed triangles and CIHE, dashed line open circles) compared to room air controls (NX, solid line closed circles). (b) Significant decrease in specific respiratory system compliance in CIHO/E and CIHE at all doses compared to room air controls. No changes were observed between CIHO (solid line, open triangles) and Nx. N=7-11 per group. p < 0.05: * CIHO/E vs NX, †CIHE vs NX.