Fig. 3. Chronic GSK3 activation enhances re-entrainment to advance in light-cycle.
(A–B) Representative double-plotted actograms of wheel-running behavior from WT (A) and GSK3-KI (B) mice undergoing a 6-hour advance in the LD cycle. Arrows indicated the first day each animal is considered re-entrained to the new LD cycle. (C) Daily activity onset (mean ± SEM) for days before and after advance in the LD cycle (day 0). Grey bars mark the times of lights-off. n = 10–12 animals per genotype.