Table 2.
Comparison of insulin and C-peptide AUC, and homeostatic model assessment (HOMA) indexes during basal and isoprenaline-stimulated conditions, n = 8.
| Control |
Cortisol |
P value control vs cortisol |
P value basal vs isoprenaline |
|||||
|---|---|---|---|---|---|---|---|---|
| Basal | ISO | Basal | ISO | Basal | ISO | Control | Cortisol | |
| Insulin (pmol/L) | 30.4 ± 6.0 | 100.4 ± 15.7 | 55.2 ± 7.4 | 206.7 ± 30.5 | 0.025 | 0.012 | 0.012 | 0.012 |
| C-peptide (pmol/mL) | 0.25 ± 0.03 | 0.47 ± 0.05 | 0.38 ± 0.04 | 0.90 ± 0.09 | 0.001 | 0.001 | < 0.0001 | < 0.0001 |
| Control | Cortisol | P value | |
|---|---|---|---|
| Δ insulin basal to ISO (pmol/L) | 70.0 ± 10.1 | 151.5 ± 28.9 | 0.012 |
| Δ C-peptide basal to ISO (pmol/mL) | 0.22 ± 0.03 | 0.52 ± 0.07 | 0.012 |
| HOMA %B | 42.2 ± 5.9 | 40.5 ± 4.5 | 0.731 |
| HOMA %S | 192.2 ± 29.5 | 105.9 ± 19.2 | 0.004 |
| HOMA IR | 0.62 ± 0.11 | 1.11 ± 0.16 | 0.016 |
Mean and SEM shown.