Figure 3.
Effects on treatment with dantrolene on muscle weight and protein degradation rates in rats bearing the AH-130 hepatoma. (A) Body weight (b.w.), gastrocnemius (GSN), soleus, and heart weight in controls and AH-130 tumor-bearing rats. The data are reported as % of controls (mean ± SD, n = 8). Significance of the differences (ANOVA): *p < 0.05 vs. controls. (B) Fractional rates of protein degradation in the gastrocnemius muscle, expressed as % day (mean ± SD, n = 8), in controls and AH-130 hosts, treated or not with dantrolene. Significance of the differences (linear regression comparison; see Materials and Methods): *p < 0.05 vs. controls.
