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. 2017 Apr 19;11:22. doi: 10.3389/fncom.2017.00022

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Copyright © 2017 Wang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Framework of the cortico-thalamic network. The network contains two components: (I) the cerebral cortex, (II) the thalamus. Neural populations include: e = excitatory pyramidal neurons (EPN); i = inhibitory interneurons (IIN); r = thalamus reticular nucleus (TRN); s = specific relay nuclei (SRN). Excitatory projections are mediated by glutamate, which are denoted by the red lines with arrow heads, while the inhibitory projections are mediated by GABA_A and GABA_B receptors, which are represented by blue solid and dashed lines with round heads, respectively.