Table 2.
Effect of ethanolic extract of Amaranthus Paniculatus on SGOT, SGPT, and CRP in alloxan-induced diabetic rats
| Groups | Dose/treatment | Level of SGOT (unit/L) | Level of SGPT (unit/L) | Level of CRP (mg/dL) |
|---|---|---|---|---|
| Normal control | Normal saline (1 mL/kg) | 73 ± 0.81* | 65.7 ± 0.84* | 35 ± 1.2* |
| Diabetic control | Tap water (1 mL/kg) | 283 ± 1.2 | 167.5 ± 0.76 | 86 ± 0.56 |
| Ethanolic extract | 100 mg/kg | 220 ± 0.83* | 125 ± 0.97* | 56 ± 0.86* |
| Ethanolic extract | 150 mg/kg | 183 ± 1.33* | 92 ± 0.97* | 46 ± 1* |
| Glibenclamide | 10 mg/kg | 107 ± 1.30* | 74 ± 0.63* | 42 ± 2.2* |
Values expressed as mean ± SEM; n = 6.
*
p < 0.01 significant vs. diabetic control.
CRP, C-reactive protein; SGOT, serum glutamic oxaloacetic transaminase; SGPT, serum glutamic pyruvic transaminase.