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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Clin Transl Endocrinol Case Rep. 2017 Jun;4:1–4. doi: 10.1016/j.jecr.2017.02.001

Figure 1.

Figure 1

Figure 1

Histological examination of the pituitary gland demonstrates areas of architectural distortion and acinar expansion with displaced reticulin network, staining positively for ACTH, with adjacent normal pituitary tissue. On Panel C, a few cells showed Crooke’s changes with replacement of cytoplasmic granules of basophil cells by homogeneous hyaline material (see arrow).

A. Pituitary Adenoma hematoxylin and eosin (H&E) 4×

B. Pituitary Adenoma with Immunostaining for ACTH 4×

C. Pituitary Adenoma H&E 40 x,

Histological examination of the thyroid gland demonstrates medullary thyroid carcinoma with characteristic nests of spindle shaped cells and amyloid deposits.

D. Medullary carcinoma of the thyroid 10×

E. Medullary carcinoma of the thyroid 20×