Table 4.
Single mutation (%) | Double mutation (%) | Triple mutation (%) | Quadruple mutation (%) | Quintuple mutation (%) | |
---|---|---|---|---|---|
Senegal | 20 | 22 | 44 | 52 | 0 |
Tanzania | 2 | 2 | 48 | 58 | 0 |
p value | 0.01 | 0.005 | 0.84 | 0.7 | 0 |
Mutant alleles from dhfr, dhps genes were combined to make the single mutation (S108N), double mutation (dhfr C59R/S108N), triple mutation (dhfr N51I/C59R/S108 N), quadruple mutation (dhfr N51I/C59R/S108N dhps A437G) and quintuple mutation (N51I/C59R/S108N dhfr and A437G/K540E dhps)