Table 4.
Distribution of the EPIC hormone bother domain items before and after 6 and 12 months of androgen-deprivation therapy
| No such symptom | No problem | Very small problem | Small problem | Moderate problem | Big problem | |
|---|---|---|---|---|---|---|
| Hot flashes* | ||||||
| Pre | 80.0% | 6.7% | 11.1% | 2.2% | 0.0% | 0.0% |
| 6Mo | 46.7% | 11.1% | 20.0% | 8.9% | 13.3% | 0.0% |
| 12Mo | 31.1% | 15.6% | 17.8% | 20.0% | 8.9% | 6.7% |
| Breast tenderness/enlargement | ||||||
| Pre | 95.6% | 2.2% | 0.0% | 0.0% | 0.0% | 2.2% |
| 6Mo | 93.3% | 4.4% | 2.2% | 0.0% | 0.0% | 0.0% |
| 12Mo | 84.4% | 8.9% | 4.4% | 2.2% | 0.0% | 0.0% |
| Loss of body hair | ||||||
| Pre | 91.1% | 6.7% | 0.0% | 0.0% | 2.2% | 0.0% |
| 6Mo | 86.7% | 6.7% | 6.7% | 0.0% | 0.0% | 0.0% |
| 12Mo | 66.7% | 15.6% | 8.9% | 6.7% | 2.2% | 0.0% |
| Feeling depressed | ||||||
| Pre | 66.7% | 8.9% | 17.8% | 4.4% | 2.2% | 0.0% |
| 6Mo | 62.2% | 17.8% | 8.9% | 6.7% | 4.4% | 0.0% |
| 12Mo | 66.7% | 17.8% | 8.9% | 6.7% | 0.0% | 0.0% |
| Lack of energy | ||||||
| Pre | 57.8% | 11.1% | 15.6% | 15.6% | 0.0% | 0.0% |
| 6Mo | 55.6% | 17.8% | 13.3% | 8.9% | 4.4% | 0.0% |
| 12Mo | 46.7% | 15.6% | 28.9% | 4.4% | 2.2% | 2.2% |
| Change in body weight | ||||||
| Pre | 84.4% | 11.1% | 4.4% | 0.0% | 0.0% | 0.0% |
| 6Mo | 57.8% | 17.8% | 15.6% | 4.4% | 2.2% | 2.2% |
| 12Mo | 62.2% | 20.0% | 11.1% | 4.4% | 0.0% | 2.2% |
*p < 0.001.