Table 2B. Allele and genotype distribution of IL-8(-251) gene polymorphisms in DR.

Genotype	SNP	Mild and moderate NPDR		High-risk PDR		OR (95% CI)	P
		n=155	%	n=169	%
	T/T	92	59.4	71	42.0	0.354 (0.162, 0.770)	0.009
	T/A	52	33.5	74	43.8	0.652 (0.294, 1.447)	0.293
	A/A	11	7.1	24	14.2	Reference
Allele
	T	236	76.1	216	63.9	1.801 (1.279, 2.538)	0.001
	A	74	23.9	122	35.1

Χ² test was used to compare the genotype and allele frequencies between mild and moderate NPDR and high-risk PDR.

The SNP is in Hardy–Weinberg equilibrium.

P-value<0.05 is considered to be statistically significant.

The odds ratio for one genotype was calculated against the AA genotypes combined.