Table 4A. Allele and gene polymorphisms of IL-8(-251) and IP-10(-1596) in DME.

Genotype	SNP	Mild EMD		Moderate EMD		Severe EMD		OR	P
		n=207	%	n=173	%	n=66	%
IL-8(-251)	T/T	106	51.2	88	50.9	34	50.8	0.899 (0.442, 1.828)	0.769
	T/A	87	42.0	73	42.2	27	41.0	0.897 (0.437, 1.841)	0.767
	A/A	14	6.8	12	6.9	5	8.2	Reference
Allele
	T	299	72.2	249	71.6	87	71.3	0.966 (0.731, 1.275)	0.806
	A	115	27.8	99	28.4	35	28.7
IP-10(-1596)	C/C	171	82.6	147	85.0	58	87.9	Reference
	C/T	34	16.4	25	14.4	7	10.6	1.474 (0.131, 1.559)	0.753
	T/T	2	1.0	1	0.6	1	1.5	2.249 (0.193, 1.626)	0.493
Allele	C	376	90.8	319	91.7	123	93.2	2.53 (0.156, 1.199)	0.513
	T	38	9.2	29	8.3	9	6.8	Reference

Χ² test was used to compare the genotype and allele frequencies between various DME.

The SNP is in Hardy–Weinberg equilibrium.

P-value <0.05 is considered to be statistically significant.