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. 2017 Apr 19;7:46565. doi: 10.1038/srep46565

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Wild-type (WT) and Zeb2-cKO (cKO) mice at 2 weeks of age. Growth retardation and local alopecia in the scalp were found in Zeb2-cKO mice. (b) Alopecia developed in the scalp, limbs, chest and abdomen of Zeb2-cKO mice at 4 weeks of age. (c) Redundant skin in the upper limb of Zeb2-cKO mice (right) at 8 weeks of age. (d) Zeb2-cKO mice (right) at 16 weeks of age showed redundant skin and hyperextensibility.