Table 2.
Performance analysis of different tests with species-specific PCR as internal control.
| Variables | ICT Malaria Combo | First Response Malaria | Microscopy | Automated hemoanalyzer (Sysmex XE-2100) |
PCR |
|---|---|---|---|---|---|
| True positive | 109 | 108 | 126 | 126 | 127 |
| True negative | 150 | 150 | 150 | 150 | 150 |
| False positive | 8 | 7 | 0 | 0 | 0 |
| False negative | 11 | 10 | 2 | 2 | 1 |
| Negative Predictive Value (95% CI) | 93.16 (90.16–96.16) | 93.75 (90.85–96.65) | 98.68 (96.31–99.60) | 98.68 (96.31–99.60) | 99.33 (99.24–99.42) |
| Positive predictive value (95% CI) | 93.16 (90.16–96.16) | 93.90 (91.10–96.70) | 99.20 (98.20–100.20) | 99.20 (98.20–100.20) | 100 |
| Sensitivity (95% CI) | 90.83 (86.83–94.83) | 91.52 (87.52–95.52) | 98.41 (96.40–100.40) | 98.41 (96.40–100.40) | 99.21 (98.20–100.20) |
| Specificity (95% CI) | 94.90 (92.30–97.50) | 95.54 (93.14–97.94) | 100 | 100 | 100 |
| Accuracy (95% CI) | 93.16 (90.16–96.16) | 92.80 (89.7–97.7) | 99.28 (97.00–101.00) | 99.28 (97.00–101.00) | 99.64 (99.57–99.71) |
| Youden's J- index | 0.86 | 0.87 | 0.98 | 0.98 | 0.99 |