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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Cancer Metastasis Rev. 2016 Dec;35(4):547–573. doi: 10.1007/s10555-016-9653-x

Table 1.

PDX collection summary

Clinical Subtypes (By Patient)
Tumor Source(s)
Race/Ethnicity (By Patient)
Academic Institution Number Of
Patients
Represented
Number of
Independent
PDX Available
Estrogen
Receptor
Positive
(Including
HER2+)
HER2
Positive
Only
"Triple
Negative"
No Data Primary Pleural
Effusion
Ascites Other
Metastatic
Site
Not
Specified
Caucasian Hispanic African
American
Continental
African
Asian Not Reported
Baylor College of Medicine (USA) 42 51 10a 5 26b 1 37 2 2 1 0 10 21 9 0 0 2
Bellvitge Institute for Biomedical
Research (SPAIN)
11 11 3c 0 8d 0 8 3 0 0 0 11 0 0 0 0 0
British Columbia Cancer Agency
(CANADA)
40 40 13 6 19 1 24 4 1 10 0 0 0 0 0 0 40
Ecole Polytechnique Federale De
Lausanne (CH)
2 2 1 0 1e 0 2 0 0 0 0 2 0 0 0 0 0
Institut Bergonié (FR) 4 4 3 1 0 0 4 0 0 0 0 0 0 0 0 0 4
Institut Curie (FR) 121 121 54 9 58f 0 111 2 0 8 0 0 0 0 0 0 121
The Jackson Laboratory (JAX) (USA) 29 32 7 1 20 1 22 0 0 4 3 21 1 0 0 2 5
MD Anderson Cancer Center (USA)
- Meric-Bernstam
26 29 13 0 13 0 24 0 0 5 0 10 2 13 0 1 0
MD Anderson Cancer Center (USA)
- Piwnica-Wormsg,h
23 26 0 0 23i 0 24 0 0 1 0 12 3 6 0 2 0
Medical Campus (USA) 25 25 11 1 12 1 20 2 2 1 0 0 0 0 0 0 25
University of Manchester Institute
of Cancer Sciences (UK)
20 20 11 1 8 0 12 1 7 0 0 18 0 0 0 0 2
University of Michigan (USA) 20 21 3 3 14 0 15 5 0 1 0 6 0 4 9 0 1
University of Utah - Huntsman
Cancer Institute (USA)
16 20 6 2 8c 0 7 9 1 3 0 14 2 0 0 0 0
Walter and Eliza Hall Institute of
Medical Research (WEHI) (AU)
59 62 19i 6 34j 0 58 0 0 1 0 0 0 0 0 0 59
Washington University (USA) 68 73 27 4 37 0 33 0 0 40 0 50 0 18 0 0 0

TOTAL 506 537 181 39 281 5 401 28 13 75 3 154 29 50 9 5 259
PERCENT OF TOTAL 36 8 56 1 30 6 10 2 1 51
a

(2 BRCA1; 1 BRCA2)

b

(4 BRCA1)

c

(1 BRCA2)

d

(1 BRCA1, 1 metaplastic, 2 metaplastic mixed ductal)

e

Medullary

f

5 BRCA1, 4 BRCA2, 4 metaplastic

g

Defined as "Stable" at passage 2

h

All treatment naïve

i

(4 BRCA1; 1 BRCA2)

j

(1 BRCA2)

k

(8 BRCA1; 1 BRCA2; 2 metaplastic)