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. Author manuscript; available in PMC: 2017 Apr 19.
Published in final edited form as: ALTEX. 2016 May 15;33(3):272–321. doi: 10.14573/altex.1603161

Fig. 13. Hard micro-machining of microfluidic plates and chips.

Fig. 13

MPS examples of a chip and a plate manufactured using thermoplastic polymers. Microscopy slide format chip with integrated fluidic interfaces (A) with cross-flow operating membranes for on-chip co-culture of cells. A microtiter plate-sized platform with on-plate reservoirs for passive hydrodynamic driven fluid flow (design HepaChip project, FKZ 031A121D) (B). Animation of an integrated MPS with parallel on-chip co-culture of different organ equivalents and on-chip liquid supply, including windows optical imaging of metabolites (C). (Courtesy of Microfluidic ChipShop, Germany.)