Table 3. Distribution of the clinical and epidemiological characteristics of individuals diagnosed with TB who underwent DST. State of Espírito Santo, Brazil, 2002 to 2012.
Characteristic | Total | Groups | pa | ||||
---|---|---|---|---|---|---|---|
| |||||||
Non-resistant | Resistant | ||||||
|
|
|
|||||
n | % | n | % | n | % | ||
Type of case | 1,575 | ||||||
New case | 74.0 | 1,083 | 77.0 | 77 | 45.0 | < 0.001 | |
Recurrence | 14.0 | 155 | 11.0 | 70 | 40.0 | ||
Re-entry after abandonment | 10.0 | 136 | 10.0 | 23 | 13.0 | ||
Transfer | 2.0 | 28 | 2.0 | 3 | 2.0 | ||
Number of previous treatments | 1,576 | ||||||
No treatment | 80.0 | 1,183 | 84.0 | 80 | 46.0 | < 0.001 | |
1 | 13.0 | 150 | 11.0 | 52 | 30.0 | ||
2 | 6.0 | 59 | 4.0 | 29 | 17.0 | ||
≥ 3 | 1.0 | 11 | 1.0 | 12 | 7.0 | ||
Chest x-ray | 1,487 | ||||||
Suspected | 98.0 | 1,298 | 98.0 | 161 | 98.0 | 0.587 | |
Normal | 2.0 | 24 | 2.0 | 4 | 2.0 | ||
Tuberculin test | 384 | ||||||
No reaction | 18 | 65 | 19 | 3 | 7 | 0.122 | |
Weak reaction | 7 | 22 | 6 | 4 | 9 | ||
Strong reaction | 76 | 253 | 74 | 37 | 84 | ||
Type | 1,575 | ||||||
Pulmonary | 94 | 1323 | 94 | 162 | 94 | 0.916 | |
Extrapulmonary | 2 | 34 | 2 | 5 | 3 | ||
Pulmonary + Extrapulmonary | 3 | 45 | 3 | 6 | 3 | ||
Sputum smear microscopy | 1,514 | ||||||
Positive | 83 | 1,121 | 83 | 143 | 85 | 0.675 | |
Negative | 17 | 224 | 17 | 26 | 15 | ||
Sputum culture | 1,124 | ||||||
Positive | 89 | 863 | 88 | 138 | 95 | 0.023 | |
Negative | 11 | 115 | 12 | 8 | 5 | ||
Other material culture | 127 | ||||||
Positive | 87 | 69 | 74 | 69 | 13 | 65 | 0.713 |
Negative | 40 | 31 | 33 | 31 | 7 | 35 | |
Ending | 1,571 | ||||||
Cure | 82 | 1,156 | 83 | 131 | 77 | < 0.001 | |
Abandonment | 8 | 108 | 8 | 11 | 6 | ||
Death by TB | 2 | 28 | 2 | 5 | 3 | ||
Death by other causes | 3 | 40 | 3 | 6 | 4 | ||
Transfer | 4 | 59 | 4 | 6 | 4 | ||
MDR-TBb | 1 | 3 | 0 | 11 | 6 |
TB: tuberculosis; MDR-TB: multidrug-resistant tuberculosis; DST: anti-tuberculosis drug susceptibility testing
a Pearson’s Chi-square Test.
b Data available in the Sistema de Informação de Agravos de Notificação (SINAN – Information System of Reportable Diseases) from 2007.