Table 4. Multiple analysis of the clinical and epidemiological characteristics associated with resistance in individuals with tuberculosis who underwent DST. State of Espírito Santo, Brazil, 2002 to 2012.
Characteristic | Crude OR | Adjusted OR | ||||
---|---|---|---|---|---|---|
|
|
|||||
p | OR | 95%CI | p | OR | 95%CI | |
Type of treatment | ||||||
New case | 1 | 1 | ||||
Recurrence | < 0.001 | 6.35 | 4.41–9.15 | < 0.001 | 7.72 | 4.24–14.05 |
Re-entry after abandonment | 0.001 | 2.38 | 1.44–3.92 | 0.001 | 3.91 | 1.81–8.43 |
Transfer | 0.508 | 1.51 | 0.45–5.07 | 0.999 | ||
Number of previous treatments* | ||||||
No treatment | 1 | |||||
1 | < 0.001 | 5.13 | 3.48–7.56 | |||
2 | < 0.001 | 7.27 | 4.41–11.97 | |||
≥ 3 | < 0.001 | 16.13 | 6.90–37.70 | |||
Alcohol | ||||||
Yes | 0.022 | 1.57 | 1.07–2.32 | 0.933 | 1.03 | 0.55–1.92 |
No | 1 | 1 | ||||
Smoking | ||||||
Yes | < 0.001 | 5.02 | 2.99–8.45 | < 0.001 | 3.93 | 1.98–7.79 |
No | 1 | 1 | ||||
Sputum culture | ||||||
Positive | 0.027 | 2.30 | 1.10–4.81 | 0.026 | 3.22 | 1.15–8.99 |
Negative | 1 | 1 |
DST: anti-tuberculosis drug susceptibility testing
* Variable is not part of the logistic regression model by collinearity.
N = 428 (27.2%)