Table 3.

Comparison of demographic variables and medication regimen complexity between patients with nonischemic cardiomyopathy versus ischemic cardiomyopathy

	NISCM (n=60)	ISCM (n=85)	P-value
Demographics
Age, years	71±7	74±8	0.05
Men	32 (53.3%)	61 (71.8%)	0.02
Caucasian	43 (71.7%)	74 (87%)	0.02
Hispanic	3 (5%)	4 (4.7%)	1
NYHA functional class
I	16 (26.7%)	8 (9.4%)	0.03
II	13 (21.7%)	27 (31.8%)
III	13 (21.7%)	27 (31.8%)
IV	18 (30%)	23 (27%)
Total medication count	12.2±4.5	14.1±4.9	0.008
Heart failure prescription count	3.2±1.2	3.2±1.4	0.51
Percentage of total medication count	26%	23%
Other prescription count	5.7±3.7	7.3±3.4	0.008
Percentage of total medication count	47%	52%
OTC medication count	3.3±2	3.6±2.6	0.37
Percentage of total medication count	27%	25%
Total pMRCI score	28.8±12.7	34.5±15.2	0.009
Heart failure prescription pMRCI score	7.3±3.4	7.2±3.4	0.99
Percentage of total pMRCI score	25%	21%
Other prescription pMRCI score	15.4±11.5	19.8±12	0.02
Percentage of total pMRCI score	53%	57%
OTC medication pMRCI score	6.1±3.5	7.5±5.6	0.05
Percentage of total pMRCI score	22%	22%
Categories
On 0–10 total medications	21 (35%)	20 (23.5%)	0.07
On 11–15 total medications	28 (46.7%)	35 (41.1%)
On ≥16 total medications	11 (18.3%)	30 (35.3%)

Notes: Data expressed as mean ± standard deviation or n (%). Medication counts and pMRCI scores were compared between groups using generalized linear model analysis, with NYHA functional class and sex as covariates.

Abbreviations: ISCM, ischemic cardiomyopathy; NISCM, nonischemic cardiomyopathy; NYHA, New York Heart Association; OTC, over-the-counter; pMRCI, patient-level Medication Regimen Complexity Index.