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. 2017 Apr 19;12(4):e0175153. doi: 10.1371/journal.pone.0175153

Fig 1. Inflammatory caspase-5 is increased and active in psoriatic skin.

Fig 1

A-C, Increased expression of IL-1β, caspase-1, caspase-5 in healthy (H) and psoriatic (P) skin analyzed by RTqPCR and normalized to PBGD. Data represent mean + SEM **, p < 0.01, Student’s t test (n = 6–8). D, Immunofluorescent staining of caspase-5 in healthy skin which was enhanced in psoriasis (n = 3), scale bar = 50μm. Representative control section stained with secondary antibody (ab) only and DAPI. E, Representative immunoblot analysis of healthy and psoriatic skin stained for caspase-5, indicated are pro-caspase-5 and active caspase-5 in psoriasis compared to healthy skin versus β-actin (n = 3).