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. 2017 Apr 19;12(4):e0175298. doi: 10.1371/journal.pone.0175298

Table 2. Baseline characteristics of study participants by sleep duration among women.

Characteristics Overall Sleep duration (hours) P for quadratic trend
≤ 5 6 7 8 ≥ 9
Number 105,974 15,378 30,413 35,442 19,602 5,139
Age (years)a 40.2 (9.7) 41.8 (11.0) 40.5 (9.6) 39.9 (9.2) 39.5 (9.5) 39.1 (10.8) <0.001
Seoul center (%) 64.6 69.4 68.8 63.8 58.4 54.1 <0.001
Obesity (%) 13.5 17.3 14.0 12.0 12.2 13.4 <0.001
Current smoker (%) 2.5 3.7 2.6 2.0 2.2 2.3 0.022
Alcohol intake (%)b 5.9 8.6 6.0 5.0 5.2 6.0 0.041
HEPA (%) 15.0 16.2 15.3 15.0 14.2 12.5 <0.001
High education (%)d 74.3 68.4 74.6 76.6 75.0 71.4 0.006
Married (%) 82.4 76.6 79.4 84.2 87.5 87.0 <0.001
Depression (%) 16.3 27.5 17.4 12.9 12.6 14.9 <0.001
Hypertension 7.0 10.0 7.1 6.0 6.4 7.0 0.038
Diabetes 2.7 3.7 2.7 2.3 2.7 3.4 0.524
History of CVD 0.9 1.4 0.9 0.8 0.8 1.1 0.021
BMI (kg/m2) 21.8 (3.0) 22.2 (3.3) 21.9 (3.1) 21.6 (2.9) 21.6 (3.0) 21.6 (3.1) <0.001
Systolic BP (mmHg)a 102.5 (12.2) 103.5 (12.8) 102.5 (12.3) 102.2 (12.1) 102.2 (12.0) 102.3 (12.0) 0.003
Diastolic BP (mmHg)a 65.5 (8.7) 66.1 (9.1) 65.5 (8.8) 65.3 (8.6) 65.2 (8.6) 65.2 (8.4) <0.001
Glucose (mg/dl)a 92.3 (12.3) 92.5 (13.1) 92.2 (12.0) 92.0 (11.5) 92.4 (12.7) 92.5 (14.3) 0.013
Total cholesterol (mg/dl)a 189.0 (33.3) 191.7 (34.1) 189.6 (33.1) 188.5 (32.8) 187.6 (33.4) 186.9 (33.8) <0.001
LDL-C (mg/dl)a 111.4 (30.4) 113.4 (31.7) 111.5 (30.4) 110.8 (29.8) 110.9 (30.3) 110.5 (30.5) 0.001
HDL-C (mg/dl)a 64.8 (14.8) 64.9 (15.3) 65.3 (14.6) 65.1 (14.6) 63.9 (14.4) 63.2 (14.4) <0.001
Triglycerides (mg/dl)c 72 (55–99) 74 (56–103) 71 (55–98) 71 (55–96) 72 (56–99) 73 (56–102) <0.001
ALT (U/l)c 13 (11–18) 14 (11–19) 13 (11–18) 13 (10–17) 13 (10–18) 13 (10–17) <0.001
HOMA-IRc 1.06 (0.71–1.55) 1.04 (0.69–1.57) 1.04 (0.70–1.54) 1.06 (0.72–1.53) 1.08 (0.73–1.57) 1.10 (0.74–1.61) <0.001
hsCRP (mg/l)c 0.3 (0.2–0.7) 0.3 (0.2–0.7) 0.3 (0.2–0.7) 0.3 (0.2–0.6) 0.3 (0.2–0.7) 0.3 (0.2–0.7) <0.001
Total energy intakec,e 1437.5 (1092.2–1810.2) 1411.9 (1052.9–1808.1) 1417.7 (1074.4–1793.4) 1443.3 (1104.3–1806.0) 1465.1 (1124.0–1824.4) 1476.4 (1107.6–1861.2) <0.001
Poor sleep quality 22.8 53.8 25.5 14.8 11.4 13.9 <0.001

Data are expressed as

a mean (standard deviation)

c median (interquartile range), or percentage.

b ≥ 20 g of ethanol per day

d ≥ college graduate

e among 165,861 participants with plausible estimated energy intake levels (within three standard deviations from the log-transformed mean energy intake).

CVD, cardiovascular disease; ALT, alanine aminotransferase; BMI, body mass index; BP, blood pressure; HDL-C, high-density lipoprotein cholesterol; HEPA, health-enhancing physical activity; hsCRP, high sensitivity C-reactive protein; HOMA-IR, homeostasis model assessment of insulin resistance.