Table 3. Prevalence ratiosa (95% CI) of CKD and glomerular hyperfiltration by sleep duration and subjective sleep quality among men.
Sleep duration (hours) | P for quadratic trend | Subjective sleep quality | ||||||
---|---|---|---|---|---|---|---|---|
≤5 | 6 | 7 | 8 | ≥9 | Good | Poor | ||
Number | 21,081 | 55,249 | 45,242 | 12,533 | 1,528 | 115,623 | 20,010 | |
CKD | ||||||||
Cases (%) | 113 (0.5) | 187 (0.3) | 210 (0.5) | 94 (0.8) | 40 (2.6) | 535 (0.5) | 109 (0.5) | |
Crude | 1.16 (0.92–1.46) | 0.73 (0.60–0.89) | Reference | 1.62 (1.27–2.07) | 5.88 (4.18–8.29) | <0.001 | Reference | 1.19 (0.97–1.46) |
Multivariate-adjusted PRsa | ||||||||
Model 1 | 1.23 (0.97–1.56) | 0.93 (0.76–1.14) | Reference | 0.98 (0.76–1.27) | 1.52 (0.76–1.13) | 0.062 | Reference | 1.09 (0.87–1.36) |
Model 2 | 1.22 (0.95–1.55) | 0.93 (0.75–1.14) | Reference | 0.97 (0.75–1.26) | 1.56 (1.06–2.30) | 0.059 | Reference | 1.06 (0.84–1.32) |
Hyperfiltration | ||||||||
Cases (%) | 1,054 (5.0) | 2,571 (4.7) | 2,184 (4.8) | 624 (5.0) | 101 (6.6) | 5,449 (4.7) | 1,085 (5.4) | |
Crude | 1.04 (0.96–1.12) | 0.96 (0.91–1.02) | Reference | 1.04 (0.95–1.14) | 1.43 (1.16–1.76) | <0.001 | Reference | 1.16 (1.09–1.24) |
Multivariate-adjusted PRsa | ||||||||
Model 1 | 1.01 (0.93–1.09) | 0.97 (0.91–1.02) | Reference | 1.03 (0.94–1.13) | 1.41 (1.14–1.74) | 0.001 | Reference | 1.10 (1.03–1.18) |
Model 2 | 1.00 (0.93–1.08) | 0.97 (0.91–1.03) | Reference | 1.03 (0.94–1.13) | 1.39 (1.13–1.72) | 0.002 | Reference | 1.09 (1.02–1.17) |
a Estimated from multinomial logistic regression models. Multivariable model 1 was adjusted for age, center, year of screening exam, smoking status, alcohol intake, physical activity, marital status, education level, total caloric intake, and depression; model 2 includes all of the variables from model 1 plus adjustment for history of diabetes, history of hypertension, and history of cardiovascular disease.
CKD, chronic kidney disease; BMI, body mass index; CI, confidence intervals; PR, prevalence ratio. CKD is defined as GFR < 60 ml/min per 1.73 m2.