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. 2017 Apr 19;12(4):e0175298. doi: 10.1371/journal.pone.0175298

Table 3. Prevalence ratiosa (95% CI) of CKD and glomerular hyperfiltration by sleep duration and subjective sleep quality among men.

Sleep duration (hours) P for quadratic trend Subjective sleep quality
≤5 6 7 8 ≥9 Good Poor
Number 21,081 55,249 45,242 12,533 1,528 115,623 20,010
CKD
  Cases (%) 113 (0.5) 187 (0.3) 210 (0.5) 94 (0.8) 40 (2.6) 535 (0.5) 109 (0.5)
  Crude 1.16 (0.92–1.46) 0.73 (0.60–0.89) Reference 1.62 (1.27–2.07) 5.88 (4.18–8.29) <0.001 Reference 1.19 (0.97–1.46)
  Multivariate-adjusted PRsa
    Model 1 1.23 (0.97–1.56) 0.93 (0.76–1.14) Reference 0.98 (0.76–1.27) 1.52 (0.76–1.13) 0.062 Reference 1.09 (0.87–1.36)
    Model 2 1.22 (0.95–1.55) 0.93 (0.75–1.14) Reference 0.97 (0.75–1.26) 1.56 (1.06–2.30) 0.059 Reference 1.06 (0.84–1.32)
Hyperfiltration
  Cases (%) 1,054 (5.0) 2,571 (4.7) 2,184 (4.8) 624 (5.0) 101 (6.6) 5,449 (4.7) 1,085 (5.4)
  Crude 1.04 (0.96–1.12) 0.96 (0.91–1.02) Reference 1.04 (0.95–1.14) 1.43 (1.16–1.76) <0.001 Reference 1.16 (1.09–1.24)
  Multivariate-adjusted PRsa
    Model 1 1.01 (0.93–1.09) 0.97 (0.91–1.02) Reference 1.03 (0.94–1.13) 1.41 (1.14–1.74) 0.001 Reference 1.10 (1.03–1.18)
    Model 2 1.00 (0.93–1.08) 0.97 (0.91–1.03) Reference 1.03 (0.94–1.13) 1.39 (1.13–1.72) 0.002 Reference 1.09 (1.02–1.17)

a Estimated from multinomial logistic regression models. Multivariable model 1 was adjusted for age, center, year of screening exam, smoking status, alcohol intake, physical activity, marital status, education level, total caloric intake, and depression; model 2 includes all of the variables from model 1 plus adjustment for history of diabetes, history of hypertension, and history of cardiovascular disease.

CKD, chronic kidney disease; BMI, body mass index; CI, confidence intervals; PR, prevalence ratio. CKD is defined as GFR < 60 ml/min per 1.73 m2.