Table S1.
Univariate and multivariate analyses of overall survival in 776 stage III patients undergoing curative resection for gastric cancer
| Characteristics | Univariate analysis
|
Multivariate analysis
|
|---|---|---|
| HR (95% CI) P-value | HR (95% CI) P-value | |
| Age (years) | <0.001 | 0.009 |
| <60 | 1 | 1 |
| ≥60 | 1.459 (1.210, 1.759) | 1.290 (1.065, 1.564) |
| Sex | 0.668 | |
| Male | 1 | |
| Female | 1.045 (0.856, 1.275) | |
| Tumor size (cm) | 0.083 | |
| <5 | 1 | |
| ≥5 | 1.183 (0.978, 1.431) | |
| Tumor location | <0.001 | <0.001 |
| Upper third | 1 | 1 |
| Middle/lower third | 0.785 (0.705, 0.874) | 0.805 (0.720, 0.900) |
| Histological grade | 0.106 | |
| Well differentiated | 1 | |
| Poorly differentiated | 1.272 (0.950, 1.704) | |
| Prognostic nutritional index | 0.005 | 0.059 |
| 0 | 1 | 1 |
| 1 | 1.455 (1.118, 1.894) | 1.299 (0.990, 1.706) |
| Performance status | 0.049 | 0.087 |
| 0 | 1 | 1 |
| 1/2 | 0.826 (0.684, 0.999) | 0.843 (0.693, 1.025) |
| Body mass index (kg/m2) | 0.035 | 0.101 |
| <18.5 | 1 | 1 |
| ≥18.5 | 0.880 (0.782, 0.991) | 0.903 (0.800, 1.020) |
| Serum albumin (g/L) | 0.008 | 0.137 |
| ≥35 | 1 | 1 |
| <35 | 1.450 (1.100, 1.911) | 1.246 (0.933, 1.663) |
| Preoperative body weight loss | 0.003 | 0.004 |
| No | 1 | 1 |
| Limited/severe | 1.227 (1.073, 1.403) | 1.223 (1.065, 1.405) |
| Depth of tumor | <0.001 | 0.002 |
| T1/T2 | 1 | 1 |
| T3/T4 | 1.540 (1.318, 1.800) | 1.375 (1.123, 1.684) |
| Levels of lymph node | <0.001 | <0.001 |
| N0/N1 | 1 | 1 |
| N2/N3 | 1.758 (1.531, 2.019) | 1.542 (1.349, 1.763) |
| Adjuvant chemotherapy | 0.005 | 0.113 |
| No | 1 | 1 |
| Yes | 0.753 (0.618, 0.916) | 0.849 (0.694, 1.040) |
Abbreviations: CI, confidence interval; HR, hazard ratio.