. 2017 Apr 19;12(4):e0175622. doi: 10.1371/journal.pone.0175622

Table 4. Predictability of the EGFR mutation status by the combinations of well-established clinical factors with or without SUV_max.

		EGFR mutation status		Sensitivity	Specificity	PPV	NPV	Accuracy
Clinical predictors		Positive	Negative
Female & Non-smoker ^*	Yes	182	115	54%	71%	61%	65%	64%
	No	152	285
Non-smoker & SUV_max ≤ 2.69	Yes	131	83	39%	79%	61%	61%	61%
	No	203	317
Female & Non-smoker	Yes	110	66	33%	84%	63%	60%	60%
& SUV_max ≤ 2.69	No	224	334

* means pack-years ≤ 5.

PPV = positive predictive value; NPV = negative predictive value.

Table 4. Predictability of the EGFR mutation status by the combinations of well-established clinical factors with or without SUVmax.