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. 2017 Apr 19;12(4):e0176143. doi: 10.1371/journal.pone.0176143

Table 4. Risk factors for survival to hospital discharge.

Univariate Multivariate
OR (95% CI) p-value OR (95% CI) p-valuea
Age 0.99 (0.97–1.01) 0.339 0.98 (0.96–1.00) 0.083
CPR at daytime 1.54 (0.81–2.95) 0.189
SAVE score before ECPR 1.06 (0.99–1.13) 0.097
Location of ECMO cannulation 0.351
 ICU 1
 Cardiac catheterization laboratory 1.19 (0.59–2.40)
 General ward 0.20 (0.03–1.63)
 Emergency department 0.74 (0.28–1.93)
 Operating room 0.40 (0.08–1.93)
SOFA score after ECPR 0.74 (0.63–0.87) <0.001 0.67 (0.55–0.81) <0.001
initial ECG rhythm 0.005 <0.001
 Asystole 1 1
 PEA 4.02 (1.14–14.12) 0.030 6.16 (1.58–24.05) 0.009
 VF/Pulseless VT 7.78 (2.11–28.64) 0.002 17.86 (4.15–76.81) <0.001
CPR to ECMO pump-on time (per minute) 0.98 (0.96–0.99) 0.005 0.97 (0.95–0.99) <0.001
BMI 0.951 0.946
 Underweight 1.17 (0.37–3.73) 0.791 1.01 (0.26–3.92) 0.992
 Normal 1 1
 Overweight 0.91 (0.45–1.84) 0.793 1.27 (0.54–2.96) 0.59
 Obese 0.77 (0.23–2.56) 0.665 0.90 (0.23–3.45) 0.872

SOFA, Sequential Organ Failure Assessment; ECG, electrocardiography; PEA, pulseless electrical activity; VF, ventricular fibrillation; VT, ventricular tachycardia; CPR, cardiopulmonary resuscitation; ECMO, extracorporeal membrane oxygenation; BMI, body mass index

aAdjusted by Age, SOFA score, initial ECG rhythm, CPR to ECMO pump-on time and BMI.