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(A) Time course of the reaction rates of MCKAT for its C6 and C4 substrates (vMCKATC6 and vMCKATC4, respectively) and of the summed activities of SCAD and MCAD on their C4 substrate (vMCADC4 + vSCADC4) after a sudden upshift of [palmitoyl-CoA]CYT from 0.1 to 60 μM. (B) Time course of regulatory metabolite contributions to vMCKATC4 after a sudden [palmitoyl-CoA]CYT increase from 0.1 to 60 μM.
