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. Author manuscript; available in PMC: 2017 Apr 19.
Published in final edited form as: Cardiovasc Pharm Open Access. 2015 Feb 26;4(1):132. doi: 10.4172/2329-6607.1000132

Figure 4. A model for the effect of AGI-1067 on LPS/TLR4-induced ASK1 activation and inflammation.

Figure 4

AGI-1067 prevents the LPS/TLR4-induced dissociation ASK1 from its inhibitor Trx1, but not from 14-3-3, leading to inhibition of inflamamtion (see Text for details).