Table 1.

Computational Model Parameters

Parameter	Value or equation	Description	Reference
rBasal	−2.67 × 10−11 [mol O2/s]	Basal respiration maximum reaction rate	Measured
rFCCP	−5.40 × 10−11 [mol O2/s]	FCCP-induced respiration maximum reaction rate	Measured
CSA	1.102 × 10−5 [m2]	Cross-sectional area of representative myobundle	Measured
t	2.5 × 10−4–7.5 × 10−4 [m]	Thickness	Measured
Volume	CSA*t	Volume of myobundle
RBasal	rBasal/Volume	Volumetric basal respiration maximum reaction rate	Measured
RFCCP	rFCCP/Volume	Volumetric FCCP-induced maximum reaction rate	Measured
Km	1.33 × 10−3 [mol/m3]	Michaelis constant, substrate concentration at which the reaction rate is half of Rmax	28
DO_muscle	2.0 × 10−9 [m2/s]	Diffusion coefficient	32
T	293.15 [K]	Temperature	Measured
Ep	0.99	Porosity	33

FCCP, carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone.