Table 1. UVB-induced hyperplasia in WT, XPA-mock-infected, and XPA-infected mice.
Hyperplasia, no. of cell layers*
|
|||
---|---|---|---|
Time after UV treatment | XPA mock | XPA + AdyXPA | WT |
24 h | 0.1 ± 0.2 | [I] 0.2 ± 0.21 | 5.2 ± 1.1 |
[BI] 8.3 ± 0.7 | |||
3 weeks | 20.2 ± 3.4 | [I] 12.1 ± 1.9 | 2.9 ± 0.5 |
[BI] 3.9 ± 1.4 | |||
2 months | 22.3 ± 2.3 | [I] 5.3 ± 1.1 | 2.1 ± 2.8 |
[BI] 2.5 ± 1.5 |
Hyperplasia is given as the number of epidermal cell layers at the indicated times after in vivo exposure to UVB. Data are means ± SEM (n ≥ 3) or variation (n = 2).