Table 2. UVB-induced SCC in WT, XPA-mock-infected, and XPA-infected mice.
| Skin neoplastic transformation as a result of UVB exposure, no. of mice affected*
|
|||
|---|---|---|---|
| Time after UV treatment | XPA mock | XPA + AdyXPA | WT |
| 2 months | 18/20 | 0/22 | 0/20 |
| 5 months | 18/18 | 0/20 | 0/18 |
Number of mice that presented persistent SCC (in situ or well differentiated) after 2 or 5 months of UV treatment per total mice UV-irradiated.