FIG. 8.

PDMS microwell culture-mediated CD38⁻ cell yield did not result in statistically significant differences in engraftment between groups. Two replicate experiments, using two different cord blood donors, are individually represented by circle or square symbols. Graphs show the percentage human engraftment (hCD45⁺) in NSG mice, detected in the (A) peripheral blood, (B) spleen, and (C) BM. Lineage composition of BM hCD45 cells, including (D) B cells (CD19⁺), (E) myeloid (CD33⁺), (F) granulocyte (CD15⁺), and (G) progenitor cells (CD34⁺). Individual mice represented as individual symbols (circles and squares represent two different cell donors). Lines are drawn at the median value. BM, bone marrow; NSG, NOD/SCID gamma.