Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
SLBP protein stability is strictly regulated by CRL2FEM1A/B/C in G1 and by SCFCyclin F in G2 phase, respectively. Of note, the stability of many key cellular regulators, including Set8, p21, Cdt1, Cdc25, Claspin and USP37, are also governed by distinct E3 ligases, such as SCF and APC/C, in different cell cycle phases to orchestrate proper cell replication and division events.
