Panel (A) depicts mean (± standard error of the mean) cortical lesion volume (mm3) at 21 days after TBI. *p < 0.05 vs. TBI + STD + VEH. No other comparisons were significant (p > 0.05). (B–E) Average sized lesions at the level of the dorsal hippocampus for the TBI + STD + VEH (same group from experiment 1), TBI + EE + VEH, TBI + STD + GAL (2 mg/kg; same group from experiment 1), and TBI + EE + GAL (2 mg/kg) groups, respectively. STD, standard; VEH, vehicle; EE, environmental enrichment; GAL, galantamine.