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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Genet Epidemiol. 2017 Feb 13;41(4):309–319. doi: 10.1002/gepi.22037

Table 2. Type I error rate of the GESE test at different significant levels.

Type I error rate of the GESE test and the weighted GESE test for genes of various sizes (10, 100 or 1000 variants) with LD=0, at different significance levels.

Significance GESE Weighted GESE
10 100 1000 10 100 1000
5 × 10−2 7.1 × 10−3 4.6 × 10−2 4.7 × 10−2 7.1 × 10−3 4.9 × 10−2 4.8 × 10−2
10−2 6.6 × 10−3 8.5 × 10−3 9.3 × 10−3 6.9 × 10−3 9.5 × 10−3 9.4 × 10−3
10−3 7.6 × 10−4 1.0 × 10−3 9.0 × 10−4 9.1 × 10−4 1.1 × 10−3 8.5 × 10−4
10−4 7.3 × 10−5 1.2 × 10−4 7.8 × 10−5 8.8 × 10−5 1.2 × 10−4 8.9 × 10−5