. Author manuscript; available in PMC: 2018 May 1.

Published in final edited form as: Clin Cancer Res. 2016 Oct 19;23(9):2154–2158. doi: 10.1158/1078-0432.CCR-16-1948

Table 1.

Initial patient characteristics (n=40)

	Patients (N=40)
Median age (range)	65 (35 - 82)
Female	14 (35 %)
Male	26 (65 %)
Del (17p) ^*	21 (52 %)
Del (11q)	12 (30 %)
Del (13q)	5 (12.5 %)
FISH negative	2 (5 %)
Mutation status IGVH (immunoglobulin heavy chain variable region)	Unmutated (33) Not done (6) Mutated (1)
	Median (range)
Prior treatments	2.0 (0 - 8)
Cycles completed	42 (2 - 49)
Median follow-up time of alive patients (months)	47 (36 - 51)
Hemoglobin (g/dL)	11.7 (6.7 - 15.6)
Platelets (10³/μL)	91.5 (36 - 242)
White blood cell count (10³/μL)	22.4 (2.2 - 297.8)
Absolute lymphocytes (10³/μL)	19.9 (0.4 - 277)

Overall, among the 40 patients, 21 were del17p by FISH, of which only 3 were del17p alone and the distribution of other FISH abnormalities in the remaining 18 patients was as follows: 1 with del11q, 1 with 11q and trisomy 12, 2 with trisomy 12, 6 with del11q and del13q and 8 with del13q. Similarly, there were 12 patients with del11q (without del17p), of which only 4 were del11q alone and 8 were del11q with del13q.