Fig. 4.

Hampered axon regeneration, but no difference in motoneuron number in β2m^-/- compared with wild-type mice at 3 weeks after a 1-mm resection of the sciatic nerve. The number of motoneurons retrogradely labeled with Fast Blue after application to the proximal stump is shown in a. The numbers are very similar in the two groups of animals. (b) The number of retrogradely labeled motonerons after application to the distal stump is significantly lower in β2m^-/- animals. The numbers from individual animals are given, with horizontal lines denoting median values.