Table 1. The large connected component (LC) size in newly defined subnetworks.
| Subnetworks | No. of proteins | No. of proteins in LC |
|---|---|---|
| Full | 4,684 | 4,597 |
| Essential | 1,180 | 914 (P < 1.4 × 10-9) |
| Nonessential | 3,504 | 2,967 (P < 1.8 × 10-2) |
| No-phenotype | 1,855 | 981 (P < 7.4 × 10-2) |
| Toxicity-modulating | 1,415 | 851 (P < 8.9 × 10-3) |
| MMS | 1,100 | 639 (P < 1.4 × 10-4) |
| 4NQO | 672 | 343 (P < 1.4 × 10-5) |
| UV | 230 | 31 (P < 3.8 × 10-5) |
| t-BuOOH | 160 | 8 (P < 0.3) |
The large connected component size in all subnetworks was larger than the average obtained from the corresponding randomized networks, except for the nonessential and no-phenotype subnetworks, which had smaller large connected component size than the average obtained from the randomized networks. P values are shown in parentheses below the values for the large connected component size.