Table 2. Network measures for the metabolic network compared with the other networks.
| Networks | No. of proteins | Average degree | Characteristic path length | No. of proteins in LC | Cavg | C > 0, % | Isolated nodes, % |
|---|---|---|---|---|---|---|---|
| Full | 4,684 | 6.1883 | 4.2383 | 4,597 | 0.0846 | 36.3 | 0 |
| Essential | 1,180 | 9.5093 | 3.9546 | 914 | 0.1879 | 44.2 | 19.9 |
| (P < 9.4 × 10-37) | (P < 6.0 × 10-22) | (P < 1.4 × 10-9) | (P < 2.0 × 10-110) | (P < 1.3 × 10-105) | (P < 1.5 × 10-12) | ||
| Noness. | 3,504 | 5.0699 | 4.3305 | 2,967 | 0.0529 | 20.7 | 11.0 |
| (P < 1.5 × 10-35) | (P < 9.4 × 10-22) | (P < 1.8 × 10-2) | (P < 2.5 × 10-13) | (P < 2.0 × 10-22) | (P < 1.5 × 10-2) | ||
| Metabolic | 508 | 4.6024 | 4.2888 | 93 | 0.0276 | 3.5 | 64.8 |
| (P < 4 × 10-4) | (P < 0.3) | (P < 0.98) | (P < 0.15) | (P < 0.8) | (P < 0.68) | ||
| No-phenotype | 1,855 | 4.3919 | 4.4128 | 981 | 0.0227 | 5.9 | 36.4 |
| (P < 1.1 × 10-6) | (P < 3.7 × 10-6) | (P < 7.4 × 10-2) | (P < 2.3 × 10-2) | (P < 3.6 × 10-4) | (P < 5.0 × 10-2) | ||
| Toxicity-modulating | 1,415 | 6.0283 | 4.2228 | 851 | 0.0584 | 16.3 | 34.5 |
| (P < 1.3 × 10-7) | (P < 6.8 × 10-6) | (P < 8.9 × 10-3) | (P < 1.9 × 10-11) | (P < 1.1 × 10-18) | (P < 2.4 × 10-2) | ||
| Metabolic-noness. | 395 | 4.6127 | 4.3158 | 21 | 0.0240 | 3.3 | 70.4 |
| (P < 0.3) | (P < 0.8) | (P < 0.85) | (P < 6 × 10-4) | (P < 1.2 × 10-3) | (P < 0.4) |
Values in bold indicate that the measured value is smaller than the one obtained by using the randomized networks; values in italics indicate that the measured value is greater than the one obtained by using the radomized networks. Noness., Nonessential.