Table 3.
Laboratory evaluation
| Test | AAV patients (N = 40) | HC (N = 38) | P |
|---|---|---|---|
| Flow cytometry | |||
| % CD4+CD28null T cells | 3.1 (0.01–85) | 0.3 (0–36) | 0.003 |
| CD4+CD28null cells/µL | 9.8 (0.02–377) | 1.5 (0–321) | 0.68 |
| ELISA | |||
| Anti-hHSP60 (U/L) | 19 (0–256) | 18 (0–491) | 0.98 |
| Positive, % | 6 (15) | 5 (13) | 1.0 |
| Anti-CMV (U/L) | 176 (0–250) | 5 (0–250) | 0.20 |
| Positive, % | 24 (60) | 18 (47) | 0.36 |
Values are given as median (range) or N (%)
AAV antineutrophil cytoplasmic-antibody-associated vasculitis, HC healthy controls, OR Odds ratio, 95% CI 95% confidence intervals, ELISA enzyme-linked immunosorbent assay, anti-hHSP60 antibodies against human Heat-Shock Protein 60, anti-CMV antibodies against cytomegalovirus