Table 1.
Parameter | Ipsilateral | Contralateral | ||
---|---|---|---|---|
Slice-by-slice | Pixel-by-pixel | Slice-by-slice | Pixel-by-pixel | |
CBFB (mL/100 g /min) | 45.1 ± 6.4* | 46.5 ± 7.3* | 50.6 ± 5.6 | 52.6 ± 6.8 |
CBFA (mL/100 g /min) | 52.8 ± 7.4*$ | 54.2 ± 8.6*$ | 63.1 ± 5.5$ | 65.7 ± 5.6$ |
Baseline V 0 (mL/100 g) | 2.54 ± 0.73*† | 1.37 ± 0.64*† | 3.08 ± 1.03† | 1.75 ± 0.72† |
After ACZ V0 (mL/100 g) | 2.55 ± 0.87*† | 1.39 ± 0.69*† | 3.59 ± 0.76† | 2.13 ± 1.07† |
CVR (%) | 17.4 ± 11.1* | 17.0 ± 12.3* | 25.5 ± 9.6 | 25.7 ± 10.5 |
Delay (s) | 2.81 ± 0.14* | 2.66 ± 0.15 | ||
CMRO2 (mL/100 g/min) | 2.87 ± 0.31* | 3.06 ± 0.32 | ||
OEF (%) | 50.7 ± 4.8* | 45.9 ± 5.7 | ||
CBV (mL/100 g) | 3.91 ± 0.70* | 3.59 ± 0.72 |
ACZ acetazolamide, CBF B baseline cerebral blood flow, CBF A cerebral blood flow after ACZ; CMRO 2 cerebral metabolic rate of oxygen, OEF oxygen extraction fraction, CBV cerebral blood volume
* P < 0.05 ipsi- vs. contra-lateral; † P < 0.05 slice-by-slice vs. pixel-by-pixel delay correction; $ P < 0.05 before and after ACZ