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Influenza infection results in a persistently altered lung transcriptome. C57BL/6 mice were infected with influenza A/PR/8/34 or control PBS vehicle for the indicated time points. Whole-lung RNA was analyzed by microarray. Differentially expressed gene numbers are depicted (J5 score >10 for day 21, J5 score >7.5 for day 35). n = 4. FLU, influenza; PBS, phosphate-buffered saline.
