Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 May;24(5):210–215. doi: 10.1101/lm.043646.116

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Richlitzki et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first 12 months after the full-issue publication date (see http://learnmem.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Figure 4. — Null epac mutants exhibit altered acquisition during single-cycle training. During single-cycle training animals receive a variable number of shock trials—the unconditioned stimulus (US)—in the presence of an olfactory cue, the conditioned stimulus (CS). (A) Scheme of single-cycle training conditions that provide ascending training trials during a fixed period of CS presentation. (B) To determine the contribution of individual trials we varied the number of trials received during training and plotted performance as a function of trial number for wild-type, rut¹ and null epac mutants. We calculated the amount of newly acquired information normalized per trial for (C) first trial, (D) second trial, (E) fifth trial, and (F) 12th trial. All data represent means ± SEM. N = 6–8. Statistical differences at the level of P ≤ 0.05 are denoted by different letters.